Abstract

Review Article

A proposed mechanism to explain increases in intracranial pressure: The concept of cerebral artery wedge pressure

DR Hamilton*, A Mitha, MG Hamilton and JV Tyberg

Published: 08 January, 2020 | Volume 5 - Issue 1 | Pages: 001-003

We hypothesize that, with elevated cerebral spinal fluid (CSF) pressure, cerebral micro-vascular obstruction and congestion may occur despite (subdural) large-vein pressures being normal. Smaller veins emptying into these larger, dura-enveloped veins are not immune to the compressive effects of elevated CSF pressure and a “Starling Resistor” mechanism might explain why elevated CSF pressures collapse these smaller veins. This small cerebral venous starling resistor compression mechanism may be the final common pathway for many patients suffering from increased CSF pressures and might also be an important contributor to impaired focal venous drainage presenting as a headache with normal venous sinus pressures.

Read Full Article HTML DOI: 10.29328/journal.jccm.1001076 Cite this Article Read Full Article PDF

Keywords:

Coronary artery bypass grafting; Longitudinal strain; Right ventricle; Circumferential strain

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Figures:

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