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Electrocardiographic criteria in founder mutations related to Arrhythmogenic cardiomyopathy

Published on: 2nd February, 2018

OCLC Number/Unique Identifier: 7347065911

Founder mutations are rare causes in arrhythmogenic cardiomyopathy including TMEM43 und phospholamban mutations. The incidence is approximately 1%. P.S358L TMEM43 mutations cause aggressive, in most cases biventricular arrhythmogenic cardiomyopathy [1], with the necessity of primary prophylactic ICD implantation in men and in women>30 years for sudden cardiac death prevention.
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